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Research · Updated 25 Oct, 10:45 pm IST

10-year-old CNN outperforms GPT-6 Astra and Claude Fable 5.1 on melanoma test

Why it matters for readers: Demonstrates that newer does not always mean better and that simple, targeted models can still outperform the latest multimodal AIs on some tasks.

  • A dermatologist compared two frontier LLMs (GPT-6 Astra, Claude Fable 5.1) to a fine-tuned Inception v3 CNN on skin lesion images.1
  • The CNN, fine-tuned for about twenty minutes on public dermatology images, correctly diagnosed 125 of 200 biopsy-proven lesions (62%).1
  • GPT-6 Astra and Claude Fable 5.1 each named the correct diagnosis for 84 and 85 of the same 200 lesions (about 42%).1
  • The test used clinical photographs and dermoscopic images drawn from the MILK10k public dataset.1

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